So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? And I think its the perfect model, which is: let the government come in when its been de-risked. This episode is informative, and I know youll get a lot of value from it. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. Its the cognitive piece so how well does your brain work as you age? LEVITT: And how much fasting does a person have to do to start getting those benefits? He is the Co-founder and Chief Medical Officer of the fasting app. Comments including unnecessary profanity will be deleted. And so many years later, as I began to actually understand the benefits of sleep, it stands alone as one of what I think of as one of the four or five pillars of longevity. [1][2] He is also the first person to make the round-trip swim from Maui and Lanai. But I still stand by the benefits of nicotine. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. into a difficult position, which is to make very incremental steps in science. According to Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, alternating between mag sulfate and mag oxide. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. And I do that in academic seminars and its incredibly embarrassing. Theres an, Tim is an early-stage investor and author of five #1 New York Times bestsellers. Because there are risks to doing this study. Saturated fat and dieta postprandial triglyceridemia is associated with cardiovascular disease risk, Why lose weight to prevent covid-19 is an inappropriate and harmful message for health influencers to be sending, Mainstream, popular health gurus peddle ineffective, dangerous, and costly products that degrade physical and financial health, Why I question the objectivity of low-carb pioneers Stephen Phinney and Jeff Volek. Its great to live until youre 90 or 100 years old, but if you spend the last 20 or 30 years in so much pain or with a neurodegenerative disease like Alzheimers, youre not really enjoying those last few decades. Explore the list of the most recommended book titles suggested by Peter Attia . Ive never really experienced nicotine. And then I would come home and I had a ritual that I would do 400 pushups every single night in sets of 50s and then go to bed and repeat. The latter is just a liquid mixture of them in a slightly different ratio that favors fructose, which makes it a little sweeter. Now, in very low doses, which is what you would get if you were eating a piece of fruit, there is no problem in eating fructose. LEVITT: And it sounds like youre doing it all with private money. [4] First wanting to become a professional boxer, he later attended Queen's University, receiving B.Sc. and holds a B.Sc. And theres no getting around that. So you took more or less the same approach to academics that you took to boxing. He attended Stanford University School of Medicine, where he received his M.D. Its the cognitive piece so how well does your brain work as you age? Why didn't you address what Nina has brought up? ATTIA: Exactly. And while learning to manage stress and overcome trauma may not be the only thing it takes to prevent Type 2 diabetes, it will definitely increase your odds of staying healthy longer. LEVITT: And did you actually do a lot of fights? Where did this drive come from? It turns out that our bodies perform a lot of glucose disposal when we sleep, so sleep is incredibly important for preventing glucose from building up in our bloodstreams. Comments are welcomed and encouraged. But I loved the benefits of nicotine.. If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. Taubes and his cofounder,. 15. I hope you loved this episode as much as I did. You went to McKinsey. Who I am. 3K? Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. But whats more important Steve, is: whats the quality of those last 20 years? Hes one of the most intelligent, curious, compassionate people Ive ever met. If you want pasta sauce, find one that has no sugar. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Right? These things have a significant impact on our lives and on our families so how can we stay healthier longer? But I certainly didnt appreciate at the time what it was doing to my health. So the other night here is a funny story, because it will come across that my daughter lives a tortured life she really does enjoy this stuff. Sleep supplement. Now to your question, I did at one point in my life, circa 2011 to 2014, spend three years in uninterrupted nutritional ketosis. Peter Attia, MD, is the President and co-Founder of the Nutrition Science Initiative (NuSI). ATTIA: So there were a lot of things that were really upsetting me at the time. Peter Attia is a Canadian-born doctor who focuses on the science of longevity. I think nicotine is a remarkable molecule. Below this, it has no benefit, above this, its toxic. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. And tell us about the longest period of time you ever spent in ketosis. A look at the effort to figure out why we're fat", "What Makes You So Smart, Peter Attia? ATTIA: Well, I think the benefits of fasting are legion. Do you recognize that in yourself? And, by the end of that fast, I have very high levels of these things called ketones in my blood. So, for example, if the argument is that the people who are most disadvantaged genetically will have the greatest benefit from change, the number I talk about with patients is probably five to seven years. I would run between five and 13 miles each morning. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. I took out a piece of Nicorette gum and I started chewing. Dr. Peters goal is to reduce those early deaths as much as possible. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. I am responding to this post because: a) Peter's post made it into my message [] Peter Attia: "I Definitely Lost a Lot of IQ Points That Day" He's been an engineer, a surgeon, a management consultant, and even a boxer. This comment policy is subject to change at any time. You got to do it.. And then we talk six months later, thats a distant memory for you. Also, I had a big fight with one of the physicians at Hopkins whos super respected and amazingly prominent. Do you have specific parenting advice that you would dole out? Peter's current diet can simplified into 3 "rules": Time Restricted Feeding Avoid Sugars, High Fructose Corn Syrup & Junk Food No Restriction on Healthy Starches and Vegetables 1) Time Restricted Feeding At the low end, Peter fasts between 14 - 16 hours each day, and at the high end, he fasts between 20 - 22 hours. It started very early. is directly causal in disease in nondiabetics; There have been no RCTs demonstrating that better glycemic control in nondiabetics leads to better outcomes, much less using CGM; There have not been any long-term studies using CGM in nondiabetics whatsoever; Some of the interventions to reduce CGM readings (say, carbohydrate restriction) also would increase postprandial triglycerides, also associated with worse outcomes; There is therefore an unclear tradeoff between hyperglycemia and hypertriglyceridemia, and that is assuming that they are each causal for bad outcomes in healthy nondiabetics; The cutoffs for unacceptable glucose excursions by Peter Attia are not based on any evidence whatsoever and are arbitrary. So I dont really chew it that much anymore, just out of sheer laziness. You remember what Im talking about? In addition to being an accomplished physician, Dr. Peter is also a successful businessman. I think most people do get a bit of a cognitive jolt from it. His post can be found here. And that ketone was a substitute fuel for glucose and for fat. My Centenarian Olympics has 18 events in it. One half of all Americans are on that spectrum. Dr. Peter Attia. LEVITT: And did that pay off when you went to surgery? And to me, we want to minimize that gap, right? Healthspan has three pieces, right? Comments containing language or concepts that could be deemed offensive will be deleted. My practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). It was about 10 things. Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. He is willing to entertain any hypothesis. Dr. Attia received his medical degree from the Stanford University School of Medicine and trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including resident of the year. I mean, this is not an unethical thing to do. I admire his dedication to becoming a kick-ass 100-year-old, and I only hope I can do the same! Born: 1973. But it could put a slightly different interpretation on it. What did your day look like? And you were like, Whats that? And I was like, Oh, I chew Nicorette gum. And you asked me if I was a smoker. You need to hit a local minima in life to make a change, if not an absolute minimum. Peter Attia is the host of The Drive podcast and . So lets say youre someone whos only going to get five and a half hours of sleep at night, which for virtually everyone is still suboptimal. ATTIA: I actually this is probably one that has changed less than most in the past decade. The first two are simple: Diet and exercise. But its something I at least pay attention to now. But not too far behind it is cancer. LEVITT: So the goal was that you wanted immediate feedback on what was going on inside your body as you did these extreme workouts that you were prone to do. So I think the whole boxing thing came from an insecurity. But I tried to build a mathematical model to address a problem in the I.C.U. And so now eating a diet thats high in fructose, again, especially liquid fructose, wreaks all metabolic destruction. So shes like, lets watch M.S.T.3.K. ATTIA: Ive come a long way since then, Steve. But Im not the person thats actually going to do these studies. And the more I learned, frankly, the less I agreed with him. Mass vaccination would interfere with this a lot. Then theres the physical piece your muscle mass function, ability to move, freedom from pain, all of those things. And during all of this intentional exercise, Dr. Peter has one thing in mind: his Centenarian Olympics. Youll be able to read more about this in Dr. Peters book when it comes out, but for now, I can tell you that the Centenarian Olympics is a series of activities that Dr. Peter wants to be able to do when he turns 100. Something about that fructose molecule is really problematic. It showed I had cerebral contusions. When we start to experience those mental health issues, we die in a sense. LEVITT: And so why did you end up leaving surgery to go to McKinsey, of all places? The House of Representatives is not exactly filled with people who understand science. And then I was going to Netflix to find it. And I am so humbled by how bad I am now. And also, what hes going to talk about in this documentary is really complicated. We talk once every six months or four months. ATTIA: But I think thats an interesting point. Dr. Peter trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year. Hes spent the last few years being mentored by the top medical scientists and now hosts The Drive, a weekly, deep-dive podcast focusing on maximizing longevity by working on physical, cognitive, and emotional health. Youre listening toPeople I (Mostly) Admire with Steve Levitt, and his conversation with physician and scientist Peter Attia. After medical school, Attia spent five years at the Johns Hopkins Hospital in Baltimore, Maryland as a general surgery resident. So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. Hes really it makes me hopeful that I got some of those genes, that I can have a shot at some of that too. And then youd just be guaranteed to get N.S.F. ATTIA: I dont know. Those three effectively make up three quarters of deaths of people who dont smoke. Dr. Peter Attia. For one thing, we can avoid looking at our electronics before bed. Well, I have six kids and I havent had a good nights sleep in 18 years. He also has a B.Sc. Throughout our lives, we experience different stressors that can cause strain on our mental health. How many other concussions I had, I dont know. But a quick 20-minute power nap is no big deal! All rights reserved. That way, we can live lives that are both long and healthy! Non-lame, weekly emails on thelatest strategies and tacticsfor increasing your lifespan, healthspan, and well-being (plus new podcast announcements). And they mightve spent the last 20 of those years in an unbelievable state of misery. All of the music you heard on this show was composed by Luis Guerra. Peter Attia talks with Steve Levitt about the problem with immortality, what's missing from our Covid response, and why nicotine is underrated. 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